The Macrocosm


juliet coates

June 15th, 2010

Plant evolution may hold the key to a new generation of food resources, according to Dr Juliet Coates who runs the Coates Lab at the University of Birmingham.

Understanding plant evolution, how plants got to the way they are, remains one of the most seriously under-investigated areas of modern biology. It’s important we do know because growing enough crops in the right places to sustain the world’s population is becoming increasingly challenging. Many of the new scientific tools that enable us to understand how bacteria, yeasts and animals work at the molecular level, including genetic engineering, can now be used to understand plant biology too.

In Dr Coates’ research group, they try to understand at the molecular level how plant cells integrate information to form a many-celled plant with specific tissues and a certain form. They focus particularly on the development of the root system, and certain families of proteins that control it.  They also study “ancient” land plants that they hope will tell us more about how more complex plants evolved. They collaborate with other research groups that work on root development and with groups that study relatives of our plant proteins that control the life cycle of the malaria parasite.

julia king

June 15th, 2010

If we are to meet the targets set by Government, we need to reduce vehicle emissions dramatically and as a matter of urgency, so says Julia King who led HM Treasury King Review and is on the Committee for Climate Change.

Professor King, Vice Chancellor of Aston University, is an engineer with over 160 published papers on fatigue and fracture in structural materials, and developments in aerospace and marine propulsion technology. She has held a number of senior posts in both industry and academia.

After sixteen years as an academic researcher and university lecturer at Cambridge and Nottingham universities, Julia King joined Rolls-Royce plc in 1994.  At Rolls-Royce she held a number of senior executive appointments, including Director of Advanced Engineering for the Industrial Power Group, Managing Director of the Fan Systems Business, and Engineering Director for the Marine Business.   In 2002 Julia became Chief Executive of the Institute of Physics, and in 2004 she returned to academia as Principal of the Engineering Faculty at Imperial College, London.  In December 2006 she became Vice-Chancellor of Aston University.

andreas hornung

June 15th, 2010

Providing everyone on the planet with sufficient energy and water is an unprecedented challenge, which will only increase with a growing population unless we find new ways of meeting this challenge. One solution, says Andreas Hornung, Professor of Chemical Engineering at Aston University, is to use biomass residue (e.g. waste wood, sewage sludge, et al) as an energy source.

Professor Hornung, who is also Head of the European Bioenergy Research Institute, has major research interests in pyrolysis processes from micro-scale to technical application, and in the thermo-chemical treatment of biomass.

tony bridgwater

June 15th, 2010

We live in a finite world with finite resources, Professor Tony Bridgwater reminds us. But there are three fundamental sources of renewable energy — the sun, the tides and heat from the earth itself. Biomass captures about three thousand EJ (exajoule) per year through photosynthesis; the future for biomass is wide open.

Tony Bridgwater is Professor of Chemical Engineering at Aston University , where he leads the Bioenergy Research Group (BERG). His current research interests are on the development of technologies for fast pyrolysis of biomass, and the production of biofuels and chemical products that can be derived from biomass and from the fast pyrolysis liquids. He is Technical Director of the SUPERGEN Bioenergy Consortium supported by the EPSRC, and contributes to several EC sponsored research projects including Dibanet, Biosynergy, Bioenergy Network of Excellence, Bioliquids CHP and Bioref-Integ. He was awarded the European Johannes Linneborn Prize in 2007 for his outstanding contribution to developing energy from biomass, and the North American Don Klass Award for Excellence in Thermochemical Science in 2009.

iain chapple

June 14th, 2010

We’re entering a new era in dental treatments because of revolutionary new understanding of the biological processes underlying oral and dental diseases. And this new understanding, say Professors Iain Chapple and Tony Smith both of whom work at the School of Dentistry at the University of Birmingham, is leading to targeted biological approaches to dentistry which have the potential to dramatically improve both diagnosis and treatment.

Iain Chapple is Professor and Head of Periodontology and Consultant in Restorative Dentistry at Birmingham Dental School. He leads a Periodontal Research team active in the investigation of the pathobiological aspects of periodontal disease and mechanistic links between periodontal inflammation and systemic inflammatory diseases. He has a strong interest in free radical and antioxidant biology.

james wolffsohn

June 14th, 2010

Over the past decade, our ability to precisely measure the dimensions of the eye have greatly improved. This means that optometrists can now make much more accurate calculations for the optimum intracular lens (IOL) power to implant. So explains Professor James Wolffsohn in The New Optimists, also making the point that such technologies could revolutionise people’s lives in developing countries where affordable spectacles are difficult to come by.

Professor Wolffsohn is one of the world’s leading researchers in optometry and Deputy Executive Dean for the School of Life and Health Sciences at Aston University.

His research and teaching interests mainly revolve around intraocular lenses, contact lenses, low vision and the measurement of accommodation, having published over 90 peer reviewed academic papers and given numerous international presentations. He is also a past President of the British Contact Lens Association. He has recently published the Low Vision Manual with Professor Jonathan Jackson and an Eye Essentials Series book Imaging.

karim raza

June 14th, 2010

Dr Karim Raza co-authored the essay Rheumatoid Arthritis — does time matter? with Chris Buckley and Andrew Filer in the book The New Optimists.

Dr Raza is a senior lecturer in the Division of Immunity and Infection at the University of Birmingham and a consultant rheumatologist at Sandwell and West Birmingham Hospitals NHS Trust.

He combines his clinical work with an active research programme in the field of rheumatoid arthritis and in particular the earliest phase of this disease. His work addresses approaches to the prediction of outcome in early inflammatory arthritis, approaches to the treatment of early rheumatoid arthritis and mechanisms of joint inflammation.


andrew filer

June 14th, 2010

Rheumatology Consultant Andrew Filer co-authored the essay Rheumatoid Arthritis — does time matter? with Chris Buckley and Karim Raza in the book The New Optimists.

Dr Filer is a Senior Lecturer at the University of Birmingham and a Consultant Rheumatologist at Sandwell and West Birmingham Hospitals NHS Trust.

nicholas james

June 10th, 2010

Nick James is at the forefront of the battle against cancer. In his paper about targeted therapies (in Part 1: Microcosm: Tackling the big challenges in The New Optimists) he explains the latest cancer treatments, particularly the success, but also the cost of targeted molecular approaches to cancer treatment.

As Professor of Clinical Oncology at the University of Birmingham and the Queen Elizabeth Hospital Birmingham, Nick James’ current research focusses on urological tumours, and he leads a number of international trials. In 1994, he co-founded the leading patient website, CancerHelpUK which has won numerous awards.

He qualified from St Bartholomew’s Hospital with the principal class prize in medicine. After general training in London and Brussels, he undertook oncology training at Hammersmith, the Royal Marsden, St Marys and St Bartholomew’s Hospitals and at the Cancer Institute, Tokyo.

early response to the scientists

June 9th, 2010

I’ve just re-read the email Keith Richards sent to me way back in July 2009, when he’d received the first batch of ~50 essays by the scientists. This is what he wrote:

“What I’m left with at the end of working closely with these papers is the conviction that your original conception is bang on: exciting things are happening . . . I’ll see what ideas I come up with for organising the collection. There are obvious topics (the brain, evolution, etc) but there are also less obvious ones that might be more revealing . . . I think we need to strike a convincing balance between scientific optimism and the sadder tone of quiet doubt in the face of human venality and incompetence. In short, I want to negotiate Pope’s “glory, jest and riddle of the world” in terms of what we have here.”