People


Chris McCabe

June 24th, 2010

The New Optimists finishes in the company of Chris McCabe inside his air-conditioned laboratory looking out on the struggle between weeds and bureaucracy as the year moves from winter towards summer.

And in this connection between the personal and the universal we touch on something at the heart of the collection, a sense of playing a part in a much bigger story.

Professor Chris McCabe‘s area of expertise is in Endocrine Cancer, researching mechanisms of thyroid, breast and colorectal tumourigenisis. He is a senior editor of Endocrine-Related Cancer, and on the Science Committee for the Society of Endocrinology. In his spare time, he writes forensic thrillers as John MackenDirty Little Lies (2007), Trial by Blood (2008), Breaking Point (2009) and Control (2010) – having previously published five novels under the name John McCabe (Stickleback, Paper, Snakeskin, Big Spender and Herding Cats).

Novels under the Microscope is an interview of Professor McCabe by LabLit while he was on a NESTA Dreamtime Fellowship in 2005.

tim mason

June 24th, 2010

Sonochemistry is concerned with understanding the effect of sonic waves and wave properties on chemical systems.

Professor Tim Mason is Director of the Sonochemistry Centre at Coventry University. It’s his contention that over-specialism  is wasteful. What excites him about his research team is that there are researchers from many disciplines — biology, chemistry, environmental science, food technology, material science and pharmacology. Sonochemistry, in his view, provides an ideal model for linking scientific disciplines to expand our knowledge. (He is also a keen fisherman . . . )

Professor Mason is President of the European Society of Sonochemistry and is the Editor in Chief of the journal Ultrasonics Sonochemistry. His research interests in sonochemistry cover environmental protection, materials processing, food processing, electrochemistry and therapeutic ultrasound.

rachel edwards

June 24th, 2010

It’s now possible to make it as a female physicist, says Dr Rachel Edwards of Warwick University. With roughly the same number of women as men at all levels from undergraduate to professor level, there are role models to look up to, knowing there’s a fair chance of success.

Dr Edwards is Assistant Professor in the Department of Physics at Warwick University. Her main research interests are in non-contact generation and detection of ultrasound using lasers and electromagnatic acoustic transducers, with applications in non-destructive testing and in low temperature measurements of phase changes in single crystals; this is under the Condensed Matter Physics group. She was a NESTA:Crucible awardee in 2007, and holds an ERC Starting Independent Researcher Grant.

Robert Berry

June 24th, 2010

Climate change is the big challenge of our time. There is growing realisaation that we are damaging our children’s chances of survival unless we act to reduce carbon and other emissions, says software engineer Professor Robert Berry.

So why might this possibly insurmountable challenge be the cause for his optimism? He’s an engineer. And engineers love problems, especially problems with lots of constraints. Devising alternative sources of energy, whilst also responding to increasing demand, is perhaps the biggest challenge facing humanity, and the constraints enormous and varied . . .

Professor Berry joined Aston University as Dean of the School of Engineering and Applied Science in 2008. Before this, he was IBM Distinguished Engineer with IBM UK in Hursley, Hampshire. His research interests lie in developing techniques for understanding and improving the performance of large complex software systems.

anthony hilton

June 23rd, 2010

The public rarely has the opportunity to visit a working laboratory. Yet what goes on in our labs and research groups will help shape the future of us all. The public engagement of science — i.e. non-scientists, ordinary men and women knowing what goes on in our labs and universities helps us all understand the societal implications of research.

This is a form of democratic empowerment, says Dr Anthony Hilton, where the agenda is in the hands of the non-expert.

Dr Hilton is a Reader in Microbiology at Aston University undertaking world-class research. He’s also heavily committed to the public engagement of science. He’s taken his professional life into our living rooms through the BBC series Grime Scene Investigation and the One Show. In 2009, he received the Society for Applied Microbiology Communication Award, and the Aston Excellence Award for his contribution to community engagement. (For an example, see Aston University’s Microbiology Roadshow.)

His current research group is working on projects including the molecular epidemiology of hospital and community MRSA, phenotypic and genotypic characterisation of Clostridium difficile, the role of flying insects in the spread of hospital-associated pathogens and Salmonella carriage in companion animals.

Anthony Hilton is on Facebook.

brian tighe

June 23rd, 2010

At the heart of Brian Tighe‘s contribution to The New Optimists, is the inspiring and in many ways astounding story of how contact lenses were invented, a testament to the persistence and invention of scientists.

Professor Tighe is leader of Biomaterials Research at Aston University. His own research focuses on the design, synthesis and applications of biomedical polymers, a significant proportion of which are hydrogels, a term frequently used to describe polymers swollen with water. Current interests include novel materials for ophthalmic applications, drug delivery systems, bioadhesive polymers, synthetic materials for articular cartilage, lung surfactant and cornea. The research is interdisciplinary and involves strong interactive connections with relevant industrial companies.

michael west

June 23rd, 2010

In the study of human behaviour, there is a new fascination with strengths, potential and values. This new orientation, says Michael West of Aston Business School,  has revealed astonishing and immensely encouraging ways to promote health and well-being among people, groups and communities.

Professor Michael West is Dean at Aston Business School. He has authored, edited or co-edited 16 books and published over 150 articles for scientific and practitioner publications as well as chapters in scholarly books.

He is a Fellow of the British Psychological Society, the American Psychological Association, the International Association of Applied Psychologists, is a Chartered Fellow of the Chartered Institute of Personal and Development. His areas of research interest are team and organisational innovation and effectiveness, particularly in relation to the organization of health services. He lectures widely both nationally and internationally about the results of his research and his ideas for developing effective and innovative healthcare organisations.

jack cohen

June 23rd, 2010

The ‘folk knowledge’ of our biological inheritance is that uncommon mutations explain diversity, and that’s why we’re different from each other. But this isn’t so. Moreover, it doesn’t begin to explain phenotypic inheritance — why it is that off-spring are like parents, how it is that when you find an old photo of Great Grandmama you notice you have her smile, hold your head in exactly the same way . . .

Internationally renown reproductive biologist, adviser on science fiction aliens, and prolific author Professor Jack Cohen has a lifetime’s work in seeking to understand how it all happens.

The triumphs of neo-Darwinism combining with Mendel’s results, later explained by chromosomes and later DNA has, he says, explained a great deal about inbred populations. But real, wild genomes – the ones that have made you and Jack Cohen and nearly every organism on the planet require new explanations . . . explanations that look likely to be made in the next couple of decades.

Dr Jack Cohen is Honorary Professor of Mathematics at Warwick University, and a Fellow of the Institute of Biology. A now-retired reproductive biologist, he published widely in academic journals. He has also written several books, and co-authored Collapse of Chaos and Figments of Reality with Professor Ian Stewart with whom he has also written several science fiction novels. Cohen and Stewart teamed with Terry Pratchett to write three Science of Discworld books.

When Terry Pratchett received an Hon DLitt from Warwick, he returned the compliment, creating Jack Cohen and Ian Stewart Honorary Wizards of the Unseen University.

susannah thorpe

June 23rd, 2010

Throughout our recent history, humans have sought both consciously and subconsciously, to identify how we differ from the rest of the animal kingdom.

Research is finally breaking down these self-created barriers, embedding humankind and our evolution soundly into the animal kingdom, says Dr Susannah Thorpe, an expert on the locomotor ecology of the great apes, including humans.

Dr Thorpe is a lecturer in Animal Behaviour at the University of Birmingham. Her research has focused on the locomotion and ecology of the great apes and in particular, the evolution of human bipedalism.(See also her work reported on the Discovery Channel, as well as the BBC.)

Her work has recently been published in Science and Proceedings of the National Academy of Science and she has presented at conferences worldwide.

peter sadler

June 23rd, 2010

The hundred or so elements of the Periodic Table determine everything we do, what our universe is made of, how the body’s biochemistry works, the drugs we take, the clothes we wear, the TV screens we watch . . . they make up the fabric, the substance of life.

Professor Peter Sadler, whose research field is inorganic chemistry, the stuff of the Periodic Table, works at the interdisciplinary borders of inorganic chemistry, biology and medicine.

Which of the 81 stable elements on earth, he asks, are essential for life? Can the genome tell us? Probably not . . . We think certain metals, for example vanadium, chromium, nickel and tin are essential, but actually we know very little about them. If they are essential, should we be using them in medicine?

The basis of many therapies are carbon (organic) compounds. Many inorganic elements, however, are more difficult to study than carbon. Professor Sadler argues that the challenges and the scope for radical discovery lie here.

Professor Peter Sadler is Head of Warwick’s Chemistry Department. His research interests are the chemistry of metals in medicine (bioinorganic chemistry, inorganic chemical biology and medicine), and the design and chemical mechanism of action of therapeutic metal complexes, including organometallic arene anticancer complexes, photoactivated metal anticancer complexes (for photochemotherapy), metallomacrocycles as antivirals and stem-cell-mobilising agents, and metalloantibiotics. Besides synthesis of co-ordination complexes, his research involves studies of interactions with targets such as RNA, DNA and proteins, and often industrial and international interdisciplinary collaborations.