Posts Tagged ‘immunology’

graham anderson

June 21st, 2010

Just how do your cells know what’s particularly you and what’s not-you? How, for all of us, do our cells discriminate between self and non-self?

Or, to put it into the more formal language of immunologists, what is the spectrum of antigens recognised by the peripheral T-cell population?

Such is the important work of Professor Graham Anderson in the School of Immunity and Infection at the University of Birmingham. And it’s complex work, requiring the input from a variety of disciplines, and from clinicians as well as pure researchers — Professor Anderson, for example, monitors how designer organs function in an in vivo setting.

In The New Optimists, Professor Anderson makes the point that it’s this very sociability of science and scientists that leads to a sharing of ideas, a key driver in developing scientific understanding.

peter lane

June 19th, 2010

The capacity to decipher the DNA encoding our genes, and techniques to make antibodies of exquisite mono-specificity are the foundations of modern molecular medicine.

Experts such as Professor Peter Lane, however, still don’t know how to allow a transplanted organ to survive indefinitely without immunosuppression of  the host, but they do know it’s an achievable goal — during pregnancy, the mother ‘tolerates’ the developing child without mounting a damaging immune response. Modern molecular medicine affords us glimpses of the processes that enable this to happen.

Peter Lane is Professor of Clinical Immunology and the MRC Centre for Immune Regulation, part of the Institute of Biomedical Research at Birmingham Medical School. He works on the molecular and cellular basis of CD4 memory as he believes that understanding these mechanisms will provide important new therapies for human diseases.